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Recent reports in Science and Medicine for April 2006

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::::::::::            April 28

:::::::::  Weekend Reading - Basic Science and general interest articles  :::::::::

1. FDA
• MedWatch: Promethazine Products Contraindicated in Children Under 2 Years. [Medcape]
2. *  Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment. [The Lancet (limited access). Reviews: ScienceNOW, Science Daily, New Scientist]
3. Effect of a US National Institutes of Health programme of clinical trials on public health and costs. Lancet. 2006 Apr 22;367(9519):1319-27. [Pubmed]
4. Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial. Intl J Obesity Online publication 18 April 2006. [Eurekalert]
5. Haplotype Insufficiency for Suppressor of Cytokine Signaling-2 Enhances Intestinal Growth and Promotes Polyp Formation in Growth Hormone-Transgenic Mice. Endocrinology 2006 147: 1632-1641.
6. Obesity, Disordered Eating, and Eating Disorders in a Longitudinal Study of Adolescents: How Do Dieters Fare 5 Years Later? J Am Dietetic Ass. 2006. [News] [Eurekalert]

::::::::::            April 27            ::::::::::

1. * An Inducible Mouse Model of Melanoma Expressing a Defined Tumor Antigen. Cancer Res 2006 66: 3278-3286.  
2. Effects of weight training on quality of life in recent breast cancer survivors. The Weight Training for Breast Cancer Survivors (WTBS) study. Cancer 2006 published online 27 March. [Medscape]
3. High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients. Cancer Cell 2006; 9: 313-325. [MedNews]
4. Archives of Internal Medicine  Vol. 166 No. 8, pp. 824-932, April 24, 2006
   • * Prevention of Relapse After Quitting Smoking: A Systematic Review of Trials. Arch Intern Med. 2006;166:828-835.
     
   • Oxycodone for Cancer-Related Pain: Meta-analysis of Randomized Controlled Trials. Arch Intern Med. 2006;166:837-843.
   • * Association of Impaired Diurnal Blood Pressure Variation With a Subsequent Decline in Glomerular Filtration Rate. Arch Intern Med. 2006;166:846-852. [Medscape]
   • Comparison of Bleeding in Patients With Nonvalvular Atrial Fibrillation Treated With Ximelagatran or Warfarin: Assessment of Incidence, Case-Fatality Rate, Time Course and Sites of Bleeding, and Risk Factors for Bleeding. Arch Intern Med. 2006;166:853-859.
   • Effect of Weight Loss and Exercise on Frailty in Obese Older Adults. Arch Intern Med. 2006;166:860-866.
   • Effects of Calcium Supplementation on Clinical Fracture and Bone Structure: Results of a 5-Year, Double-blind, Placebo-Controlled Trial in Elderly Women. Arch Intern Med. 2006;166:869-875.
   • Depressive Symptoms After Acute Myocardial Infarction: Evidence for Highest Rates in Younger Women. The PREMIER Registry Investigators. Arch Intern Med. 2006;166:876-883.
   • Proteinuria and Risk for Stroke and Coronary Heart Disease During 27 Years of Follow-up: The Honolulu Heart Program. Arch Intern Med. 2006;166:884-889.
   • Prospective Study of Health Status Preferences and Changes in Preferences Over Time in Older Adults. Arch Intern Med. 2006;166:890-895.
   • Racial Differences in Trust in Health Care Providers. Arch Intern Med. 2006;166:896-901.
   • Effects of Etanercept in Patients With the Metabolic Syndrome. Arch Intern Med. 2006;166:902-908.
   • Prognostic Impact of Prolonged Ventricular Repolarization in Hypertension. Arch Intern Med. 2006;166:909-913.
   • Predicting Medical and Surgical Complications of Carotid Endarterectomy: Comparing the Risk Indexes. Arch Intern Med. 2006;166:914-920.
   • End-of-Life Decision Making in Europe and Australia: A Physician Survey. The European End-of-Life (EURELD) Consortium. Arch Intern Med. 2006;166:921-929.

::::::::::            April 26            ::::::::::

1. * Variant Creutzfeldt-Jakob disease: prion protein genotype analysis of positive appendix tissue samples from a retrospective prevalence study. BMJ (published 10 April 2006)
2. Bone-patellar tendon-bone autografts versus hamstring autografts for reconstruction of anterior cruciate ligament: meta-analysis. BMJ (published 7 April 2006)
3. * Active and passive smoking and development of glucose intolerance among young adults in a prospective cohort: CARDIA study. BMJ (published 7 April 2006)
4. Early determinants of physical activity in adolescence: prospective birth cohort study. BMJ, (published 6 April 2006)
5. New England Journal of Medicine  Volume 354 April 20, 2006 Number 16
   • Private Health Care in Canada. R. Steinbrook
   • The NIH Budget and the Future of Biomedical Research. J. Loscalzo
   • * Statistics and Medicine: The Challenge of Subgroup Analyses — Reporting without Distorting. S. W. Lagakos
   • * Efficacy and Safety of Corticosteroids for Persistent Acute Respiratory Distress Syndrome. The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network [Medscape]
   • Feasibility of Treating Prehypertension with an Angiotensin-Receptor Blocker. S. Julius and Others
   • Oral Ondansetron for Gastroenteritis in a Pediatric Emergency Department. S. B. Freedman, M. Adler, R. Seshadri, and E. C. Powell [Medscape]
   • * Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events. D. L. Bhatt and Others
   • Scabies. O. Chosidow
   • Lung Inflammation in ARDS — Friend or Foe? P. M. Suter
   • Pharmacotherapy for Prehypertension — Mission Accomplished? H. Schunkert
   • The Charisma of Subgroups and the Subgroups of CHARISMA. M. A. Pfeffer and J. A. Jarcho

::::::::::            April 25            ::::::::::

1. *  The Antimicrobial Treatment Strategies (MIKSTRA) Program: A 5-Year Follow-Up of Infection-Specific Antibiotic Use in Primary Health Care and the Effect of Implementation of Treatment Guidelines. The MIKSTRA Collaborative Study Group. Clin Inf Dis 2006;42:1221-1230. [Eurekalert]
2. High Rate of Spontaneous Negativity for Hepatitis C Virus RNA after Establishment of Chronic Infection in Alaska Natives. Clin Infect Dis 2006;42:945-954. UpToDate Topic Review: Clinical features and natural history of hepatitis C virus infection. [Medscape]
3. JAMA Vol. 295 No. 15, pp. 1741-1860, April 19, 2006
   • Neuropsychological and Renal Effects of Dental Amalgam in Children: A Randomized Clinical Trial. JAMA. 2006;295:1775-1783.
   • Neurobehavioral Effects of Dental Amalgam in Children: A Randomized Clinical Trial. JAMA. 2006;295:1784-1792.
   • Education, 15-Year Risk Factor Progression, and Coronary Artery Calcium in Young Adulthood and Early Middle Age: The Coronary Artery Risk Development in Young Adults Study. JAMA. 2006;295:1793-1800.
   • Second-Order Peer Review of the Medical Literature for Clinical Practitioners. The McMaster Premium Literature Service (PLUS) Project. JAMA. 2006;295:1801-1808.
   • Reviews: Birth Spacing and Risk of Adverse Perinatal Outcomes: A Meta-analysis. JAMA. 2006;295:1809-1823.
   • Clinical Review: The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295:1824-1830.
   • Commentaries: Will Physician-Level Measures of Clinical Performance Be Used in Medical Malpractice Litigation? JAMA. 2006;295:1831-1834.
   • Editorials: Mercury in Dental Amalgam—A Neurotoxic Risk? JAMA. 2006;295:1835-1836.
   • Birth Spacing—The Long and Short of It. JAMA. 2006;295:1837-1838.

::::::::::            April 24            ::::::::::

1. Targeting the inflamed synovium: The quest for specificity. Arth & Rheum 2006; 54: 1055-1060. [Eurekalert]
2. * Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6. Arth & Rheum 2006; 54: 1222-1232. [Eurekalert]
3. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL. J Orthopaedic Res 2006; 24: 820-830. [Getting ACL tears to heal themselves- Growth-factor-rich gel regenerates knee ligament, with 40% increase in strength. [Eurekalert]
4. A randomised controlled trial evaluating the effects of two workstation interventions on upper body pain and incident musculoskeletal disorders among computer operators. Occup Environ Med 2006; 63: 300-306. [Eurekalert]
5. Annals of Internal Medicine  18 April 2006 Volume 144 Issue 8 Previous Issue
   • Does Utilization of Screening Mammography Explain Racial and Ethnic Differences in Breast Cancer? R. Smith-Bindman, and Others.
   • The Relationship between Green Tea and Total Caffeine Intake and Risk for Self-Reported Type 2 Diabetes among Japanese Adults. The JACC Study Group*
   • Telephone Care Management To Improve Cancer Screening among Low-Income Women: A Randomized, Controlled Trial. Allen J. Dietrich, and Others.
   • Brief Communication: Atrial–Esophageal Fistulas after Radiofrequency Ablation. Jennifer E. Cummings and Others.
   • Medicine and Public Issues: Research Misconduct, Retraction, and Cleansing the Medical Literature: Lessons from the Poehlman Case. Harold C. Sox and Drummond Rennie
     
   • Clinical Guidelines: Risk Assessment for and Strategies To Reduce Perioperative Pulmonary Complications for Patients Undergoing Noncardiothoracic Surgery: A Guideline from the American College of Physicians
   • * Preoperative Pulmonary Risk Stratification for Noncardiothoracic Surgery: Systematic Review for the American College of Physicians. [Eurekalert]
   • * Strategies To Reduce Postoperative Pulmonary Complications after Noncardiothoracic Surgery: Systematic Review for the American College of Physicians.
   • Editorial: Exploring and Crossing the Disparity Divide in Cancer Mortality. Mary B. Barton

::::::::::            April 21

:::::::::  Weekend Reading - Basic Science and general interest articles  :::::::::

1. FDA
   • MedWatch:
     • Macugen (pegaptanib ) Important changes in the approved product labeling. Rare reports of anaphylaxis/anaphylactoid reactions, including angioedema following the administration of Macugen along with various medications administered as part of the injection preparation. [Medscape]
     • Fungal Keratitis Infections Related to Contact Lens Use. Medwatch [Medscape]
     • FDA News: Investigation of Serious Eye Infections Associated With Soft Contact Lens Use and Contact Lens Solution. Consumers Are Advised to Follow Good Hygiene Practices and Manufacturers’ Instructions to Prevent Infection. [Medscape]
   • FDA Safety Changes: Naprosyn/Anaprox and Other Prescription NSAIDs [Medscape]
   • FDA Approvals: Orphan Drug [Medscape]
     • Lestaurtinib (CEP-701 ) for the treatment of acute myeloid leukemia (AML).
     • TRX4 (hAglyCD3) for the treatment of new-onset type 1 diabetes mellitus.
     • EPI-A0001 for the treatment of inherited mitochondrial respiratory chain diseases.
   • Summary View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) -- January 2006
2. Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior. Nature: Medicine Published online: 9 April 2006.
3. Induction of leptin resistance through direct interaction of C-reactive protein with leptin. Nature Medicine 12, 425 - 432 (2006). [Eurekalert: Clues to obesity’s cause ]
4. * Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome. Science 7 April 2006 312: 117-121. [Eurekalert and Medscape reviews]

   Podcast  suggestion:	New England Journal of Medicine audio
   	Find out more about podcasting on the iTunes site or see the Wikipedia definition.

::::::::::            April 20            ::::::::::

1. Randomized clinical trial comparing surgery with conservative treatment for uncomplicated varicose veins. Br J Surg. 2006; 93(2):175-81 [Medscape review]
2. Indomethacin and Celecoxib Impair Rotator Cuff Tendon-to-Bone Healing. Am J Sports Med 2006 34: 362-369. [Medscape]
3. Archives of Internal Medicine Vol. 166 No. 7, pp. 708-812, April 10, 2006
   • Editorial: The Role of Fibrates in a Statin World. Arch Intern Med. 2006;166:715-716.
   • Review: Antiarrhythmic Drugs for Maintaining Sinus Rhythm After Cardioversion of Atrial Fibrillation: A Systematic Review of Randomized Controlled Trials. Arch Intern Med. 2006;166:719-728.
   • Risk of Recurrent Venous Thromboembolism in Patients With Common Thrombophilia: A Systematic Review. Arch Intern Med. 2006;166:729-736.
   • Attenuation of Progression of Insulin Resistance in Patients With Coronary Artery Disease by Bezafibrate. Arch Intern Med. 2006;166:737-741.
   • Gemfibrozil in the Treatment of Dyslipidemia: An 18-Year Mortality Follow-up of the Helsinki Heart Study. Arch Intern Med. 2006;166:743-748.
   • Terminal Sedation and Euthanasia: A Comparison of Clinical Practices. Arch Intern Med. 2006;166:749-753.
   • Adoption of Patient-Centered Care Practices by Physicians: Results From a National Survey. Arch Intern Med. 2006;166:754-759.
   • A Prospective Study of Female Hormone Use and Breast Cancer Among Black Women. Arch Intern Med. 2006;166:760-765.
   • Early Ambulation After Hip Fracture: Effects on Function and Mortality. Arch Intern Med. 2006;166:766-771.
   • Venous Thrombosis and Conjugated Equine Estrogen in Women Without a Uterus. Arch Intern Med. 2006;166:772-780. [Medscape]
   • Hyponatremia and Long-term Mortality in Survivors of Acute ST-Elevation Myocardial Infarction. Arch Intern Med. 2006;166:781-786.
   • Angiotensin-Converting Enzyme Inhibitors in Patients With Coronary Artery Disease and Absence of Heart Failure or Left Ventricular Systolic Dysfunction: An Overview of Long-term Randomized Controlled Trials. Arch Intern Med. 2006;166:787-796.
   • Differing Effects of Antihypertensive Drugs on the Incidence of Diabetes Mellitus Among Patients With Hypertensive Kidney Disease.
     Arch Intern Med. 2006;166:797-805.
   • Clopidogrel to Treat Patients With Non–ST-Segment Elevation Acute Coronary Syndromes After Hospital Discharge. Arch Intern Med. 2006;166:806-811.

::::::::::            April 19            ::::::::::

1. * Initial Results of the Study of Tamoxifen and Raloxifene (STAR) Released: Osteoporosis Drug Raloxifene Shown to be as Effective as Tamoxifen in Preventing Invasive Breast Cancer. NIH News report [Medscape]
2. New England Journal of Medicine Volume 354 April 13, 2006 Number 15
   • After the Storm — Health Care Infrastructure in Post-Katrina New Orleans. R. E. Berggren and T. J. Curiel
   • Adaptations. R. E. Berggren
   • Access to the Scientific Literature — A Difficult Balance. M. Frank
   • Abdominal Sacrocolpopexy with Burch Colposuspension to Reduce Urinary Stress Incontinence. L. Brubaker and Others
   • Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease. The Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators
   • Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction. K. H. Bønaa and Others
   • The Effect of Telithromycin in Acute Exacerbations of Asthma. S. L. Johnston and Others
   • Medical Progress: Trans Fatty Acids and Cardiovascular Disease. D. Mozaffarian and Others
   • Placement of an Arterial Line. K. Tegtmeyer and Others. Video
   • Pellagra-like Dermatitis. N. Ashourian and N. Mousdicas
   • Pseudoclubbing. A. Farzaneh-Far
   • The Vexing Problem of Hidden Incontinence. R. G. Rogers
   • Homocysteine Trials — Clear Outcomes for Complex Reasons. J. Loscalzo
   • Treating Acute Asthma with Antibiotics — Not Quite Yet. F. F. Little
   • Videos in Clinical Medicine — A New Journal Feature. G. T. McMahon, J. R. Ingelfinger, and E. W. Campion
   • A Toggle for Type 2 Diabetes? B. Thorens

::::::::::            April 18            ::::::::::

1. Epstein-Barr Virus Tied to Multiple Sclerosis in Long-Term Study. Arch Neurol 2006;63:E1-E5.[Medscape]
2. JAMA Vol. 295 No. 14, pp. 1619-1730, April 12, 2006
   • * Effects of Conjugated Equine Estrogens on Breast Cancer and Mammography Screening in Postmenopausal Women With Hysterectomy. JAMA 2006;295:1647-1657. [Medscape]
   • * Estrogen-Receptor Status and Outcomes of Modern Chemotherapy for Patients With Node-Positive Breast Cancer. JAMA 2006;295:1658-1667.
   • * Invasive Pneumococcal Disease Among Infants Before and After Introduction of Pneumococcal Conjugate Vaccine. JAMA 2006;295:1668-1674.
   • Effect of Blinded Peer Review on Abstract Acceptance. JAMA 2006;295:1675-1680.
   • * Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes. JAMA. 2006;295:1681-1687.
   • Assessing Glycemia in Diabetes Using Self-monitoring Blood Glucose and Hemoglobin A1c. JAMA. 2006;295:1688-1697`
   • Public Health Strategies for Pandemic Influenza: Ethics and the Law. JAMA. 2006;295:1700-1704.
   • Recent Trials in Hypertension: Compelling Science or Commercial Speech? JAMA. 2006;295:1704-1706.
   • Editorial: Glycemic Variability: A Hemoglobin A1c–Independent Risk Factor for Diabetic Complications. JAMA 2006;295:1707-1708.
   • From the Archives Journals: The Hidden and Potent Effects of Television Advertising. JAMA 2006;295:1698-1699.

::::::::::            April 12            ::::::::::

1. Randomized clinical trial comparing surgery with conservative treatment for uncomplicated varicose veins. Br J Surg. 2006; 93(2):175-81 [Medscape review]
2. Indomethacin and Celecoxib Impair Rotator Cuff Tendon-to-Bone Healing. Am J Sports Med 2006 34: 362-369. [Medscape]

::::::::::            April 11            ::::::::::

1. Mitigation strategies for pandemic influenza in the United States. PNAS 2006; published online April 3. [Medscape] [LiveScience animation]
2. New England Journal of Medicine Volume 354 April 6, 2006 Number 14
   • * ADHD Drugs and Cardiovascular Risk. S. E. Nissen
   • The Changing Face of Teenage Drug Abuse — The Trend toward Prescription Drugs. R. A. Friedman
   • Research on Stroke: Small Vessels, Big Problems. S. M. Greenberg [Medscape]
   • * Effect of Introduction of the Pneumococcal Conjugate Vaccine on Drug-Resistant Streptococcus pneumoniae. M. H. Kyaw and Others [Medscape]
   • * Comparison of Fondaparinux and Enoxaparin in Acute Coronary Syndromes. The Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators
   • * Enoxaparin versus Unfractionated Heparin with Fibrinolysis for ST-Elevation Myocardial Infarction. E. M. Antman and Others
   • Brief Report: Role of COL4A1 in Small-Vessel Disease and Hemorrhagic Stroke. D. B. Gould and Others
   • Sexual Desire and Arousal Disorders in Women. R. Basson
   • Current Concepts: The Biology of Human Sex Differences. D. D. Federman
   • Pneumococcal Vaccine — Direct and Indirect ("Herd") Effects. D. M. Musher
   • Therapy for Patients with Acute Coronary Syndromes — New Opportunities. R. J. Gibbons and V. Fuster

::::::::::            April 10            ::::::::::

1. ß-Glucan incorporated into a fruit drink effectively lowers serum LDL-cholesterol concentrations. Am J Clin Nutr 2006;83:601-605. [Medscape]
2. JAMA Vol. 295 No. 13, pp. 1481-1612, April 5, 2006
   • Effects of Fondaparinux on Mortality and Reinfarction in Patients With Acute ST-Segment Elevation Myocardial Infarction: The OASIS-6 Randomized Trial. The OASIS-6 Trial Group*. JAMA. 2006;295:1519-1530.
   • Abciximab in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention After Clopidogrel Pretreatment: The ISAR-REACT 2 Randomized Trial. Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment 2 (ISAR-REACT 2) Trial Investigators. JAMA. 2006;295:1531-1538.
   • * Effect of 6-Month Calorie Restriction on Biomarkers of Longevity, Metabolic Adaptation, and Oxidative Stress in Overweight Individuals: A Randomized Controlled Trial. Pennington CALERIE Team. JAMA. 2006;295:1539-1548. [Medscape] [NYTimes]
   • * Prevalence of Overweight and Obesity in the United States, 1999-2004. JAMA. 2006;295:1549-1555.
   • * Preliminary Communications: Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial. ASTEROID Investigators. JAMA. 2006;295:1556-1565.
   • The Rational Clinical Examination: Can the Clinical History Distinguish Between Organic and Functional Dyspepsia? JAMA. 2006;295:1566-1576.
   • * Editorials: Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 2006;295:1577-1578.
     
   • Fondaparinux in ST-Segment Elevation Myocardial Infarction: The Drug, the Strategy, the Environment, or All of the Above? JAMA. 2006;295:1579-1580.
   • Clopidogrel Treatment Prior to Percutaneous Coronary Intervention: When Enough Isn't Enough. JAMA. 2006;295:1581-1582.
   • Can a Potent Statin Actually Regress Coronary Atherosclerosis? JAMA. 2006;295:1583-1584.

::::::::::            April 7

:::::::::  Weekend Reading - Basic Science and general interest articles  :::::::::

1. FDA
   1. MedWatch: Ontak (denileukin diftitox) warning of the risk for visual loss associated with use. [Medscape]
   2. FDA Approvals: Orphan Drug Approvals: [Medscape]
      • Ceflatonin (homoharringtonine) for the treatment of chronic myeloid leukemia (CML).
      • Valortim ( MDX-1303) for the treatment of anthrax infection.
      • TQ-1018 (topical capsaicin) for the management of postherpetic neuralgia.
   3. The FDA has warned of flagrant violations of donor screening regulations by BioMedical Tissue Services, Inc. which have brought the safety of implanted tissues into question. [Medscape]
2. Tissue-Engineered Bladders Successfully Implanted Into 7 Patients Needing Cystoplasty [Medscape from April 4 Lancet (limited access)]
3. Acute Infections May Raise Risk of Venous Thromboembolic Events [Medscape review from Lancet 2006;367:1075-1079. (limited access)]
4. Religious Attendance: More Cost-Effective Than Lipitor? D. E. Hall. J Am Board Family Med 19:103-109 (2006). [BBC News]
5. Intellectual ability and cortical development in children and adolescents. Nature 440, 676-679 (30 March 2006) [Brain Development Linked to IQ. ScienceNOW]
6. Time for the renaissance of medicine in the Middle East. The Lancet 2006; 367:959

::::::::::            April 6             ::::::::::

1. News in Cardiology
   • *  Low-Density Lipoprotein and High-Density Lipoprotein Particle Subclasses Predict Coronary Events and Are Favorably Changed by Gemfibrozil Therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Circulation. 2006;113:1556-1563.
   • *  Editorial: Cardioprotective Properties of Fibrates -Which Fibrate, Which Patients, What Mechanism? Circulation. 2006;113:1553-1555.
   • Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults. Circulation 2006: published online March 27, 2006 [Medscape]
   • Personal health habits of american cardiologists. Am J Cardiol. 2006 Apr 1;97(7):1093-6.
   • *  Impaired Capacity for Stimulated Fibrinolysis in Primary Hypertension Is Restored by Antihypertensive Therapy. Hypertension. 2006;47:686.
   • Endothelium-Derived Epoxyeicosatrienoic Acids and Vascular Function. Hypertension. 2006;47:629.
   • *  Sport practice and the risk of lone atrial fibrillation: A case–control study. Intl J Cardiol 2006;108: 332-337.
   • Population-Based Analysis of Sudden Cardiac Death With and Without Left Ventricular Systolic Dysfunction: Two-Year Findings from the Oregon Sudden Unexpected Death Study. J Am Coll Cardiol 2006;47:1161-1166. [Medscape]
   • *  Obstructive Sleep Apnea Syndrome: More Insights on Structural and Functional Cardiac Alterations, and the Effects of Treatment With Continuous Positive Airway Pressure. J Am Coll Cardiol 2006 47: 1433-1439. [Eurekalert]
   • Effects of Normal Aging on Left Ventricular Lusitropic, Inotropic, and Chronotropic Responses to Dobutamine. J Am Coll Cardiol 2006 47: 1440-1447.
   • Robotic Magnetic Navigation for Atrial Fibrillation Ablation. J Am Coll Cardiol 2006 47: 1390-1400. [Eurekalert]
   • *  Cholesteryl Ester Transfer Protein (CETP) Inhibition Beyond Raising High-Density Lipoprotein Cholesterol Levels: Pathways by Which Modulation of CETP Activity May Alter Atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 2006;26:706.
   • Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non-musicians: the importance of silence. Heart 2006;92:445-452. Editorial: The sound of silence is music to the heart . Heart 2006;92:433-434.
   • * B-type natriuretic peptide identifies silent myocardial ischaemia in stroke survivors. Heart 2006;92:487-489. [Medscape]
   • Left ventricular function after exercise training in young men. Am J Cardiol. 2006; 97:1089-92.
   • * Long-Term Caloric Restriction Ameliorates the Decline in Diastolic Function in Humans. J Am Coll Cardiol 2006 47: 398-402.

::::::::::            April 5            ::::::::::

1. Infectious mononucleosis and risk for multiple sclerosis: A meta-analysis. Ann Neurol 2006;59:499-503. [Medscape]
2. Anxiety and stress in the postpartum: is there more to postnatal distress than depression? BMC Psychiatry 2006, 6:12. [Medscape]
3. Chronic stress at work and the metabolic syndrome: prospective study. BMJ 2006;332:521-525. [Medscape]
4. Is There Cross-Reactivity Between Penicillins and Cephalosporins? Am J Med 2006 119: 354.
5. Annals of Internal Medicine 4 April 2006 Volume 144 Issue 7
   • Improvements in Diabetes Processes of Care and Intermediate Outcomes: United States, 1988–2002. J. B. Saaddine, and Others. [Medscape]
   • Therapy Modifications in Response to Poorly Controlled Hypertension, Dyslipidemia, and Diabetes Mellitus. N. Rodondi, and Others.
   • *  Effects of Comprehensive Lifestyle Modification on Diet, Weight, Physical Fitness, and Blood Pressure Control: 18-Month Results of a Randomized Trial. P. J. Elmer, and Others.
   • Outcomes of Minor and Subsyndromal Depression among Elderly Patients in Primary Care Settings. J. M. Lyness, and Others.
   • Brief Communication: Sirolimus-Associated Pneumonitis: 24 Cases in Renal Transplant Recipients. L. Champion, and Others.
     
   • Improving Patient Care : Computerization Can Create Safety Hazards: A Bar-Coding Near Miss. C. J. McDonald
     
   • Reviews: Adiposity of the Heart*, Revisited. J. M. McGavock, and Others
     
   • Editorials: Improving the Outcomes of Metabolic Conditions: Managing Momentum To Overcome Clinical Inertia. J. B. Perlin and L. M. Pogach
   • Minor Depression: Midway between Major Depression and Euthymia. K. Kroenke
     
   • On Being a Doctor: The Pediatric Arrest. A. A. Peterson

::::::::::            April 4            ::::::::::

1. * Antiinflammatory Effects of Salmeterol/Fluticasone Propionate in Chronic Obstructive Lung Disease. Am. J. Respir. Crit. Care Med. 2006; 173: 736-743. [Eurekalert]
2. Brain Natriuretic Peptide Is a Prognostic Parameter in Chronic Lung Disease. Am. J. Respir. Crit. Care Med. 2006; 173: 744-750. [Eurekalert]
3. * Novel Endovascular Treatment of Blunt Thoracic Aortic Trauma with a Self-Expanding Stent Lined with Aortic Extender Cuffs. J. K. Thompson, and Others. Annals Vasc Surg 2006; online. [News: Surgeons have developed a new, minimally invasive method for repairing blunt thoracic aortic trauma injuries.]
4. Archives of Internal Medicine Vol. 166 No. 6, pp. 598-696, March 27, 2006
   • Editorials: Time, Now, to Recover the Fun in the Physical Examination Rather Than Abandon It. Arch Intern Med. 2006;166:603-604.
     
   • Commentaries: Reconsidering Medication Appropriateness for Patients Late in Life. Arch Intern Med. 2006;166:605-609.
   • *  Competency in Cardiac Examination Skills in Medical Students, Trainees, Physicians, and Faculty: A Multicenter Study. Arch Intern Med. 2006;166:610-616.
   • *  Relationship Between Accurate Auscultation of a Clinically Useful Third Heart Sound and Level of Experience. Arch Intern Med. 2006;166:617-622.
     
   • A Trial of Disclosing Physicians' Financial Incentives to Patients. Arch Intern Med. 2006;166:623-628. [Medscape]
   • Associations Between the Age at Diagnosis and Location of Colorectal Cancer and the Use of Alcohol and Tobacco: Implications for Screening. Arch Intern Med. 2006;166:629-634.
   • Current Antibiotic Therapy for Isolated Urinary Tract Infections in Women. Arch Intern Med. 2006;166:635-639.
   • Management of Acute Pharyngitis in Adults: Reliability of Rapid Streptococcal Tests and Clinical Findings. Arch Intern Med. 2006;166:640-644. [Medscape]
   • Prolonged Effects of a Home-Based Intervention in Patients With Chronic Illness. Arch Intern Med. 2006;166:645-650.
   • Natural History of Knee Cartilage Defects and Factors Affecting Change. Arch Intern Med. 2006;166:651-658.
   • Effects of Angiotensin-Converting Enzyme Inhibition With Perindopril on Left Ventricular Remodeling and Clinical Outcome: Results of the Randomized Perindopril and Remodeling in Elderly With Acute Myocardial Infarction (PREAMI) Study. The PREAMI Investigators* Arch Intern Med. 2006;166:659-666.
   • A Controlled Trial of Naltrexone Augmentation of Nicotine Replacement Therapy for Smoking Cessation. Arch Intern Med. 2006;166:667-674. [Medscape]
   • Effect of Quality Improvement on Racial Disparities in Diabetes Care. Arch Intern Med. 2006;166:675-681.
   • Type 2 Diabetes Mellitus in Midlife Estimated From the Cambridge Risk Score and Body Mass Index. Arch Intern Med. 2006;166:682-688.
   • Use of a Blood Glucose Monitoring Manual to Enhance Monitoring Adherence in Adults With Diabetes: A Randomized Controlled Trial. Arch Intern Med. 2006;166:689-695. [Medscape]

::::::::::            April 3            ::::::::::

1. Infectious Disease News
   • Prolonged Illness after Infectious Mononucleosis Is Associated with Altered Immunity but Not with Increased Viral Load. J.I.D. 2006;193:664-671. [MedNews]
   • Eligibility for Treatment of Hepatitis C Virus Infection among Young Injection Drug Users in 3 US Cities . Clin Infect Dis 2006;42:669-675. [Medscape]
   • Bad Bugs Need Drugs: An Update on the Development Pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Inf Dis 2006;42:657-668.
   • * Clinical efficacy of anti-pneumococcal vaccination in patients with COPD. Thorax 2006; 61: 189-195. [Medscape]
   • * Synchrony, Waves, and Spatial Hierarchies in the Spread of Influenza. Science 2006; Published Online March 30, 2006. [Medscape]
2. New England Journal of Medicine   Volume 354 March 30, 2006 Number 13
   • Politics and Independence — The Collapse of the Canadian Medical Association Journal. M. Shuchman and D. A. Redelmeier
   • Part "D" for "Defective" — The Medicare Drug-Benefit Chaos. J. Avorn
   • Safety and Immunogenicity of an Inactivated Subvirion Influenza A (H5N1) Vaccine. J. J. Treanor and Others
   • *  Outpatient Gatifloxacin Therapy and Dysglycemia in Older Adults. L. Y. Park-Wyllie and Others
   • Prevalence of Monoclonal Gammopathy of Undetermined Significance. R. A. Kyle and Others ]
   • Brief Report: Recessive Symptomatic Focal Epilepsy and Mutant Contactin-Associated Protein-like 2. K. A. Strauss and Others
   • Behavioral Health Insurance Parity for Federal Employees. H. H. Goldman and Others
   • Mechanisms of Disease: Hereditary Proteinuria Syndromes and Mechanisms of Proteinuria. K. Tryggvason, J. Patrakka, and J. Wartiovaara
   • Vaccines against Avian Influenza — A Race against Time. G. A. Poland
   • Serious Adverse Drug Effects — Seeing the Trees through the Forest. J. H. Gurwitz
   • Better Behavioral Health Care Coverage for Everyone. S. Glied and A. Cuellar
   • Targeting Rickettsia. D. H. Walker

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